Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		epidermal growth factor receptor 0.295 0.885 0.37
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 0.985 1270 31 1988 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53 		tumor protein p53 0.236 0.962 0.53
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 0.941 524 31 1989 2020
Entrez Id: 238
Gene Symbol: ALK
ALK 		ALK receptor tyrosine kinase 0.396 0.846 3.2E-06
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 0.982 279 2 2008 2020
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 0.979 241 4 1993 2020
Entrez Id: 29126
Gene Symbol: CD274
CD274 		CD274 molecule 0.324 0.923 1.9E-02
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 0.977 171 0 2015 2020
Entrez Id: 4233
Gene Symbol: MET
MET 		MET proto-oncogene, receptor tyrosine kinase 0.380 0.846 0.97
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 1.000 110 3 2000 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		cyclin dependent kinase inhibitor 2A 0.300 0.885 0.39
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 0.962 104 4 1994 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 0.970 101 5 1989 2020
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		signal transducer and activator of transcription 3 0.320 0.923 1.00
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 1.000 97 1 2006 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 0.969 96 3 1996 2020
Entrez Id: 6794
Gene Symbol: STK11
STK11 		serine/threonine kinase 11 0.435 0.808 0.99
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 0.984 61 1 2003 2020
Entrez Id: 260431
Gene Symbol: COPD
COPD 		Pulmonary disease, chronic obstructive, severe early-onset 0.456 0.885
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 0.982 57 0 1986 2020
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		cyclin D1 0.344 0.923 0.89
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 1.000 49 1 1990 2020
Entrez Id: 6098
Gene Symbol: ROS1
ROS1 		ROS proto-oncogene 1, receptor tyrosine kinase 0.439 0.885 1.6E-72
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 0.980 49 0 2000 2020
Entrez Id: 1136
Gene Symbol: CHRNA3
CHRNA3 		cholinergic receptor nicotinic alpha 3 subunit 0.588 0.692 1.4E-07
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 1.000 48 15 2008 2020
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		insulin like growth factor 1 0.318 0.885 0.27
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 1.000 38 0 2000 2020
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10 		H3 histone pseudogene 10 0.350 0.846
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 0.971 35 0 1995 2020
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1 		single-strand-selective monofunctional uracil-DNA glycosylase 1 0.322 0.923 4.5E-04
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 1.000 35 0 2017 2020
Entrez Id: 1401
Gene Symbol: CRP
CRP 		C-reactive protein 0.299 0.962 3.7E-03
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 0.964 28 0 2006 2020
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		interferon gamma 0.288 0.962 0.47
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 0.920 25 0 2004 2020
Entrez Id: 1137
Gene Symbol: CHRNA4
CHRNA4 		cholinergic receptor nicotinic alpha 4 subunit 0.492 0.808 8.5E-05
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 1.000 23 3 2010 2020
Entrez Id: 7298
Gene Symbol: TYMS
TYMS 		thymidylate synthetase 0.425 0.846 0.72
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 0.913 23 0 2003 2020
Entrez Id: 7965
Gene Symbol: AIMP2
AIMP2 		aminoacyl tRNA synthetase complex interacting multifunctional protein 2 0.393 0.923 8.0E-03
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 1.000 22 0 2008 2020
Entrez Id: 857
Gene Symbol: CAV1
CAV1 		caveolin 1 0.388 0.885 8.3E-03
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 0.955 22 2 1999 2020
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3 		erb-b2 receptor tyrosine kinase 3 0.448 0.808 1.7E-15
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		disease 0.100 None 0.950 20 0 1995 2020